Abstract Description
Institution: Universidade Federal do Rio de Janeiro - Rio de Janeiro, Brazil
Oxaliplatin (OXA) chemotherapy is associated with painful peripheral neuropathy, a well-known and relevant side effect caused by mitochondrial dysfunction in sensory nerves. The transfer of functional exogenous mitochondria (mitotherapy) into mitochondria-defective cells is a promising therapeutic strategy for mitochondrial diseases. Herein, we investigated the effect of mitotherapy on oxaliplatin-induced painful peripheral neuropathy in mice.
Presenters
Authors
Authors
Robson da Costa - Universidade Federal do Rio de Janeiro , João R. L. C. B. Maia - Universidade Federal do Rio de Janeiro , Loreena K. Alves - Universidade Federal do Rio de Janeiro , Leticia M. S. Antonio - Universidade Federal do Rio de Janeiro , Lilian C. Colodeti - Universidade Federal do Rio de Janeiro , Giselle F. Passos - Universidade Federal do Rio de Janeiro , Claudia P. Figueiredo - Universidade Federal do Rio de Janeiro
