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International Association for the Study of Pain

Neuropathic pain in a prediabetic rat model developed with a low concentration of streptozotocin. - FR23

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Abstract Description

Institution: Cinvestav, IPN - Mexico, México

In this work we standardize a model of prediabetes in Wistar rats by administering a single low dose of streptozotocin. The rats in this model developed painful neuropathy, which may be useful to evaluate the cellular and molecular mechanisms underlying this pathology.

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First author Nara Alvarado-Cervantes - Cinvestav, IPN , co-authors Vladimir Martínez-Rojas - Cinvestav, IPN , Co-author Vinicio Grandos-Soto - Cinvestav, IPN , Senior author Rodolfo Delgado-Lezama - Cinvestav, IPN , Co-author Victor Tsutsumi-Fujiyoshi - Cinvestav, IPN , Co-author Silvia Galindo-Gómez - Cinvestav, IPN , Co-author Guadalupe Raya-Tafolla - Cinvestav, IPN , Co-author Guadalupe Vidal-Cantu - Cinvestav, IPN , Ricardo Felix - Cinvestav, IPN , Oscar Arias-Carrion - Unidad de Trastornos del Movimiento y Sueño, Hospital General Dr. Manuel Gea González, Ciudad de México, México. , Emmanuel Ortega-Robles - Unidad de Trastornos del Movimiento y Sueño, Hospital General Dr. Manuel Gea González, Ciudad de México, México.

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